The electrophysiology core facility (ePHYS) has acquired a high-density multielectrode array (HD-MEA) based on CMOS technology and provide services around this innovative technology.

Equipment

Accura 3D	BioCAM DupleX

• 4096 electrodes for simultaneous extracellular recording
• Suitable for neuronal cell culture, brain organoids and brain slices
• Upgrade with 3D-electrode chip for a deep access of cerebral organoids and other tissues

The core facility uses the HD-MEA system from 3Brain.

Readouts

• Spike
• Local field potential (LFP)

Assays

• Functional characterization of 2D and 3D models of human iPSCs
• Phenotyping screening
• Neuronal network activity
• Synaptic plasticity

Highlights

Services

• Generation of full data set: experimental design, data acquisition and analysis
• Access to the facility setup for trained electrophysiologists
• Training in electrophysiology
• Development of new assays on demand